Examining the use of Silodosin in treating BPH

Silodosin treats Benign Prostatic Hyperplasia (BPH). The prostate gland resides beneath the bladder, and BPH becomes a problem as men age.

Understanding BPH

Benign prostatic hyperplasia is a noncancerous enlargement of the prostate gland in men.

The prostate undergoes two distinct growth phases as a man ages. The first happens when the prostate doubles in size during early puberty. The second phase of a man’s growth begins at about age 25 and lasts most of his life. In many cases, benign prostatic hyperplasia arises during the second growth phase.

Uses and Applications

Silodosin is typically prescribed for treating BPH in adult men, also known as an enlarged prostate. The medicine reduces BPH symptoms and improves the ability to urinate in older men.

Silodosin belongs to the class of medications known as Alpha-1 blockers found in the prostate and bladder. These blockers are responsible for their contraction to relax the smooth muscles of the prostate and bladder.

When the prostate is enlarged, the urethra constricts, impairing the capacity to pee. It results in symptoms such as midnight urination, frequent and sudden urge to urinate, difficulty initiating urination, a sensation of urine retention in the bladder, leakage after urination, and the need for more effort to urinate.

Silodosin should be administered based on the patient’s age, the ailment being treated, and the severity of the condition.

Caution in Use

  • Silodosin can interact with other drugs; therefore, it should only be administered under close medical supervision. It may interact with certain blood pressure medications such as calcium channel blockers, immune-suppressing drugs, and blood pressure medications.
  • Silodosin should be avoided in the event of a severe allergic reaction, interaction with alcohol, renal or liver disease, hypotension, pregnancy and lactation, and in senior adults and children.

Side Effects

  • Common Silodosin side effects include dizziness, diarrhoea, headache and a blocked nose due to a cold.
  • Serious side effects can occasionally occur, including facial swelling, difficulty breathing or swallowing, itching and hives with skin rash, fainting, a rapid heartbeat, pale stool colour, and extremely dark urine.
  • Other uncommon symptoms include prolonged erections, a significant drop in blood pressure, dizziness, and fainting.

Special Considerations

  • The medicine should be taken with food, as taking it on an empty stomach may cause a fast drop in blood pressure or any of the aforementioned adverse effects.
  • The medication should be consumed whole without being broken or chewed.
  • The medication should be stored at room temperature, free from moisture and light.
  • Avoid overmedication, missing doses and abrupt withdrawal of the drug.

Silodosin is a prescription medication that should be taken with considerable caution to treat adult men with benign prostatic hyperplasia.

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Shubham Pharmachem is a merchant export and distribution organisation with core competencies in Active Pharmaceutical Ingredients (API), herbal extracts, nutraceutical and nutricosmetic ingredients, and research-based formulations, and providing its services to other pharmaceutical companies since the 1990s. The company caters to over 70 countries and is committed to providing innovative solutions. High professional standards, combined with diversification and business expansion, have propelled the group turnover by 400% within ten years. Committed to the highest standards of healthcare, Shubham Pharmachem has earned the trust of its national and global clientele through its strong company values of ethics, reliability and responsibility.

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Shubham Pharmachems blog posts have been written with the information gathered from approved medical journals and websites online. Our research and technical teams strive to provide relevant information through such articles. We strongly advise readers not to consume or administer medication without their doctors prior consultation.


  1. https://www.healthline.com/health/drugs/silodosin-oral-capsule#important-warnings
  2. https://www.drugs.com/sfx/silodosin-side-effects.html